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From γράφω(gráphō, “I write”) + -μα(-ma, result noun suffix).
About its weight meaning there are two theories:
It was taken from Latin scrūpulus, which in its meaning, "smallest division of weight", was more frequently written scrūpulum, scrīpulum, and by some fancied derivation from scrīptum was written scrīptulum, scrīptlum. Hence it was later translated in Ancient Greek as γράμμα from γράφω(gráphō, “to write”), as scrīptulum from scrībō(“to write”).