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An R with a cross-stroke indicating an abbreviation (of recipe, response, retrograde etc). In the case of a prescription, abbreviating Latinrecipe(“take this”, second-person singular imperative of recipiō); it is sometimes typeset as, or even interpreted as, a digraph Rx. Compare also Dx(“diagnose, diagnosis”) and Hx(“history”).
1583, Philip Barrough [i.e., Philip Barrow], “Of Making Bolus”, in The Methode of Phisicke, Conteyning the Causes, Signes, and Cures of Inward Diseases in Mans Body from the Head to the Foote., London: Thomas Vautroullier, →OCLC, book VI, page 288:
BOlvs in Engliſh is called a morſell. It is a medicine laxatiue, in forme & faſhion it is meanely whole, & it is ſwallowed by litle gobbets. […]℞. medulla caſiæ fiſtulæ newly drawen. ℥. j. or ʒ. x. the graines (that is the kernelles) of barbaries. ℈. ß. and with ſugar roſet [sugar compounded with rose petals] make a bole.
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