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1605
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15th c.
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16th c.
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17th c.
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18th c.
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19th c.
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20th c.
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1605, Francis Bacon, The Advancement of Learning:Consubstantialls are willingly intertained with a kindly embrace, and properly intenerate and supple; penetrating and insinuating remedies are the defferents, as it were, of malacissant and mollifying qualities, and convay more easily and impressedly the virtue thereof ; and doe themselves somewhat expand and open the parts.