Horner-Wadsworth-Emmons reaction
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English
Etymology
In 1958, Leopold Horner published a modified Wittig reaction using phosphonate-stabilized carbanions. William S. Wadsworth and William D. Emmons further defined the reaction.
Noun
Horner-Wadsworth-Emmons reaction (plural Horner-Wadsworth-Emmons reactions)
- A chemical reaction used in organic chemistry of stabilized phosphonate carbanions with aldehydes (or ketones) to produce predominantly E-alkenes.
Alternative forms
- HWE reaction (initialism)