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English
Noun
ICK (plural ICKs)
- (biochemistry) Initialism of inhibitor cystine knot.
2022 June 10, Oliveira, A.L., Viegas, M.F., da Silva, S.L. et al., “The chemistry of snake venom and its medicinal potential”, in Nature Reviews Chemistry, volume 6, →DOI, page 451:The composition of the venoms of the first three is dominated by short (3–9-kDa) disulfide-rich peptides that contain the inhibitor cysteine knot (ICK) motif, although heavier proteins, including enzymes, are also present. ICK peptides are structurally very stable and mainly target the nervous system, acting primarily on membrane channels or neuronal receptors3,4,5.