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Borrowed from Latinsānctus(“holy”), the opening word of the prayer in that language. The prayer is taken from Isaiah 6:3 and Matthew 21:9. Doublet of saint.
1981, H. E. G. Wegman, “Une Anaphore incomplète? Les Fragments sur Papyrus Strasbourg Gr. 254”, in R. van den Broek, M. J. Vermaseren, editors, Studies in Gnosticism and Hellenistic Religions, page 432:
Le point douteux est la fin du texte : une doxologie ‘finale’ avant le Sanctus.
The point that is dubious is the end of the text: a ‘final’ doxology before the Sanctus.