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Tea room discussion
Latest comment: 14 years ago5 comments2 people in discussion
For (deprecated template usage)with that seems like too narrow a usage example. I think the sense of with is something like "in relation to":
What's up with the new banner? / What's with the new banner?
What's happening with the health-care vote? / What's with the health-care vote?
In this usage with is unstressed.
But there is also a usage in which with (or its object) is heavily stressed (as I hear it in the US), which may be the same as what you are referring to. I think it is not exactly "wrong with", but perhaps someone else can find wording for this sense of with.