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1997, Roy Porter, The Greatest Benefit to Mankind, Folio Society, published 2016, page 443:
In cells infected with the herpes virus, acyclovir is converted to a metabolic blocking agent, thereby largely overcoming the old and plaguing problem of toxicity to the host.
From the description, Letha felt sure Jane had herpes zoster, or shingles, which often strikes cancer patients or others with depressed immune systems. Jane spent another week in the Bubble, treated with acyclovir.