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Learned borrowing from Latincarcinōma(“tumour; ulcer; carcinoma”), from Ancient Greekκᾰρκῐ́νωμᾰ(karkínōma, “sore, ulcer; cancer”), from καρκινοῦν(karkinoûn, “to make (something) resemble a crab”), καρκινοῦσθαι(karkinoûsthai, “to become cancerous; to suffer from cancer”, passive) + -μᾰ(-ma, suffix attached to verbs to form neuternouns denoting the effect or result of an action, a particular instance of an action, or the object of an action). Καρκινοῦν(Karkinoûn) is derived from καρκῐ́νος(karkínos, “crab; the zodiac sign Cancer; sore, ulcer; cancer”) (according to Paul of Aegina (c. 625 – c. 690) in his Medical Compendium in Seven Books, because the veins surrounding a cancerous tumour resemble a crab’s legs), ultimately from Proto-Indo-European*(s)ker-(“to bend; to turn”) (as a crab’s pincers form a circle) + *-iHnos(suffix forming adjectives of materials). The English word is a doublet of cancer, and may be analysed as carcino- + -oma.
Take the fatteſt and fulleſt Figs you can get, lay them upon the ugly and ill favored tumor called Carcinoma, i. the Canker, ſo it be not yet exulcerat, I aſſure you it is a ſoveraine remedie, and hardly can be matched againe: […]