centroblast

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English

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Etymology

From centro- +‎ -blast.

Pronunciation

  • IPA(key): /ˈsɛntɹəblæst/, /-blɑːst/

Noun

centroblast (plural centroblasts)

  1. (anatomy) An activated B cell that is enlarged with multiple eccentric nucleoli and proliferating in the germinal center of a secondary lymphoid follicle, after stimulation by follicular dendritic cell cytokines and helper T cells.
    • 1975, K Lennert, “Morphology and classification of malignant lymphomas and so-called reticuloses”, in Malignant Lymphomas of the Nervous System:
      Therefore we proposed the term centroblast instead of germinoblast and the term centrocyte instead of germinocyte.

Derived terms

See also