citrullination
Hello, you have come here looking for the meaning of the word citrullination. In DICTIOUS you will not only get to know all the dictionary meanings for the word citrullination, but we will also tell you about its etymology, its characteristics and you will know how to say citrullination in singular and plural. Everything you need to know about the word citrullination you have here. The definition of the word citrullination will help you to be more precise and correct when speaking or writing your texts. Knowing the definition ofcitrullination, as well as those of other words, enriches your vocabulary and provides you with more and better linguistic resources.
English
Etymology
From citrulline + -ation.
Noun
citrullination (plural citrullinations)
- (biochemistry) The posttranslational modification of the amino acid arginine in a protein into the amino acid citrulline.
- Synonym: deimination
- 2017, B. Amin, W. Voelter, “Human Deiminases”, in A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Jun'ichi Kobayashi, editors, Progress in the Chemistry of Organic Natural Products, Volume 106, Springer, page 220:
- Naturally occurring/substituted amino acids, flanking targeted arginine, influence its susceptibility to citrullination by peptidylarginine deiminases.
- 2017, Alastair Wilkins, Progressive Multiple Sclerosis, 2nd edition, Springer, page 141:
- In MS citrullination is the most studied PTM[post-translational modification] from those listed in Table 6.1.
- 2019, Shuzheng Song, Yingyan Yu, Progression on Citrullination of Proteins in Gastrointestinal Cancers, Zhe-Sheng Chen, Jian-ye Zhang, Yunkai Zhang, Yan-yan Yan (editors), Targeted Cancer Therapies, From Small Molecules to Antibodies, Frontiers Media, page 162,
- The exact effect of citrullination of proteins on cancer should be studied further.
- Citrullination of proteins is not only detected in in vitro experiments, but also in human blood.