Hello, you have come here looking for the meaning of the word
frameshift. In DICTIOUS you will not only get to know all the dictionary meanings for the word
frameshift, but we will also tell you about its etymology, its characteristics and you will know how to say
frameshift in singular and plural. Everything you need to know about the word
frameshift you have here. The definition of the word
frameshift will help you to be more precise and correct when speaking or writing your texts. Knowing the definition of
frameshift, as well as those of other words, enriches your vocabulary and provides you with more and better linguistic resources.
English
Etymology
frame + shift
Noun
frameshift (countable and uncountable, plural frameshifts)
- A frameshift mutation.
Verb
frameshift (third-person singular simple present frameshifts, present participle frameshifting, simple past and past participle frameshifted)
- To use a starting point for translating a series of nucleotides that is off by an amount not divisible by three, resulting in an entirely distinct set of codons.
2003, Jacques Lapointe, Lea Brakier-Gigras, Translation Mechanisms, →ISBN, page 354:Commonly, there are stimulatory signals in mRNA distinct from the shift site that greatly increase the level of frameshifting at the shift site.
2004, DNA and Cell Biology - Volume 23, page 702:Considering these costs, it seems likely that mechanisms may exist to stop frameshifted translation as soon as possible, depending on the frequency of occurrence.
2006, De-Shuang Huang, George William Irwin, Computational Intelligence and Bioinformatics, →ISBN:Ribosomal frameshifting at a particular site can yield two protein products from one coding sequence or one protein product from two overlapping open reading frames.