holoprosencephaly
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English
Etymology
From Ancient Greek ὅλος (hólos, “whole”) + πρόσω (prósō, “forwards, onwards”) (referring to the prosencephalon (“forebrain”)) + ἐγκέφαλος (enképhalos, “brain”) + English -y (suffix denoting a condition), i.e. “condition of a whole (inappropriately divided) forebrain”. By surface analysis, holo- + pro- + -s- + encephal- + -y.
Pronunciation
- Rhymes: -ɛfəli
Noun
holoprosencephaly (countable and uncountable, plural holoprosencephalies)
- (teratology) A congenital disorder involving insufficient division of the lobes of the brain during fetal development, resulting in skull and facial deformities ranging from minor cleft lip problems to cyclopia, in which a single eye develops where the nose would normally be.
Synonyms
- HPE (abbreviation)
Hyponyms
Coordinate terms
- Classifications of holoprosencephaly
- Associated facial deformities
Derived terms
- HPE (abbreviation)
Related terms
Translations
a congenital disorder involving insufficient division of the lobes of the brain
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References
- NINDS Holoprosencephaly Information Page at the (U.S.) National Institutes of Health