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Used by Paracelsus to refer to ladanum gum, and to a compound recipe containing pearls, but apparently not to any preparation of opium; this modern sense was introduced by his followers (Sigerist 1941:540–1).
Ever since my recovery from the fever I had been in the custom of taking every night a small quantity of laudanum; for it was by means of this drug only that I was enabled to gain the rest necessary for the preservation of life.
Whipping and abuse are like laudanum; you have to double the dose as the sensibilities decline.
2016 October 16, Dan Chiasson, “The Man Who Invented the Drug Memoir”, in The New Yorker:
At the time, Wilson writes, England was “marinated in opium, which was taken for everything from upset stomachs to sore heads.” It was swallowed in the form of pills or dissolved in alcohol to make laudanum, the tincture preferred by De Quincey.
2020 November 13, Ligaya Mishan, “Once the Disease of Gluttonous Aristocrats, Gout Is Now Tormenting the Masses”, in The New York Times, →ISSN:
In Sydenham’s 1683 treatise on the disease, for the sudden onset of violent symptoms he recommended laudanum — a tincture of opium and alcohol — to take the edge off the pain; […]
laudanum in Charles du Fresne du Cange’s Glossarium Mediæ et Infimæ Latinitatis (augmented edition with additions by D. P. Carpenterius, Adelungius and others, edited by Léopold Favre, 1883–1887)