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An insane person, especially one who suffers from a mania.
She was driving like a maniac.
2017 October 18, Seth Kubersky, “A weekend full of puppetry-themed entertainment is just the ticket, unless you’re pupaphobic”, in Orlando Weekly:
Hey kids, the word of the week is "pupaphobia"! Others may enjoy being frightened by chainsaw-wielding maniacs and cannibal clowns, but my Halloween is never complete without a murderous Muppet or two. Thankfully, a pair of events last Friday the 13th provided a perfect double feature of puppet perversity.
2017, J. C. Staudt, Children of the Wastes:
“It gives me the dithers, thinking of the damage that maniac could do if he ever took the headship. He could reinstate the cycle of chosen births, or enact any of a hundred other terrible laws.”