obinutuzumab
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English
Etymology
From + -tu- (“tumor”) + -zumab (“humanized monoclonal antibody”).
(This etymology is missing or incomplete. Please add to it, or discuss it at the Etymology scriptorium.)
Noun
obinutuzumab (uncountable)
- (pharmacology) Synonym of afutuzumab.
- 2015 July 23, “Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities”, in PLOS ONE, :
- Recently, mogamulizumab (anti-CCR4 antibody, Kyowa Hakko Kirin) and obinutuzumab (anti-CD20 antibody, Genentech/Roche) with depleted core fucoses have been approved for marketing, and several glycoengineered antibodies are in clinical studies and are being developed as next generation therapeutic monoclonal antibodies.