warfarin
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English
Etymology
From Wisconsin Alumni Research Foundation + (coum)arin.
Pronunciation
- (Received Pronunciation) IPA(key): /ˈwɔː.fə.ɹɪn/
- (General American) IPA(key): /ˈwɔɹ.fəɹ.ɪn/
Noun
warfarin (countable and uncountable, plural warfarins)
- (pharmacology) A coumarin salt, warfarin sodium, found in certain clovers, that retards blood coagulation:
- 2015 July 29, Carville G. Bevans et al., “Phylogeny of the Vitamin K 2,3-Epoxide Reductase (VKOR) Family and Evolutionary Relationship to the Disulfide Bond Formation Protein B (DsbB) Family”, in Nutrients, volume 7, :
- In the case of pathological hypercoagulative conditions such as thrombosis and embolism, 4-hydroxycoumarin based oral anticoagulants, including warfarin as a well-known example, are administered to block the enzymatic function of VKORC1, effectively diminishing turnover of the vitamin K cycle.
- Manufactured as a pharmaceutical drug and used in low dosage, with regular monitoring, for the prevention of thrombosis and embolism.
- Manufactured as a chemical, used in high dosage as a pesticide.
Derived terms
Translations
anticoagulant
See also
References
- “warfarin”, in Lexico, Dictionary.com; Oxford University Press, 2019–2022.
- “warfarin”, in Merriam-Webster Online Dictionary, Springfield, Mass.: Merriam-Webster, 1996–present.