zalcitabine

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English

Molecular structure of zalcitabine
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Alternative forms

Etymology

From +‎ -citabine (cytarabine or azacytidine derivative).

(This etymology is missing or incomplete. Please add to it, or discuss it at the Etymology scriptorium.)

Pronunciation

Noun

zalcitabine (countable and uncountable, plural zalcitabines)

  1. (pharmacology) A drug C9H13N3O3 which inhibits the replication of HIV and is formerly used in the treatment of AIDS, especially in combination with zidovudine. It is a synthetic analog of a pyrimidine nucleoside, acting as a reverse transcriptase inhibitor.
    • 1997 July 4, B. Autran et al., “Positive Effects of Combined Antiretroviral Therapy on CD4 T Cell Homeostasis and Function in Advanced HIV Disease”, in Science, volume 277, number 5322, →DOI, pages 112–116:
      Patients received 600 mg/day of ritonavir (Abbott Laboratories) for 14 days, after which were added 600 mg/day of zidovudine (Retrovir, Glaxo-Wellcome) and 6 mg/day of zalcitabine (Hivid, Roche) with treatment maintenance for 12 months.

References

Italian

Noun

zalcitabine f

  1. plural of zalcitabina