depeptidize

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English

Etymology

From de- +‎ peptide +‎ -ize.

Verb

depeptidize (third-person singular simple present depeptidizes, present participle depeptidizing, simple past and past participle depeptidized)

  1. (transitive, biochemistry, organic chemistry) To remove the peptide bonds from.
    • 2013 September 15, Anita Y. M. Howe, Srikanth Venkatraman, “The Discovery and Development of Boceprevir: A Novel, First-generation Inhibitor of the Hepatitis C Virus NS3/4A Serine Protease”, in Journal of Clinical and Translational Hepatology, volume 1, →DOI:
      By introducing peptide isosteres, modifying the side chains of amino acids, and methylating amide nitrogens to depeptidize the molecule, the methylated Analog 7 was identified []