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1916, William Phillips Graves, Gynecology, page 188:
Esthiomene simulates in its appearance cancer and lupus, from which it should always be distinguished by a microscopic examination of a section of tissue. There are inflammations of the vulva, especially in neglected gonorrhea cases ...
1933, U.S. Public health service, The Journal of Venereal Disease Information..., page 302:
In men chronic ulcers of the penis sometimes occur which are analogous to esthiomene in women and they too may be accompanied by anorectal stricture.
1950, Chronicle of the World Health Organization:
The tertiary stage is marked by symptoms such as esthiomene, urethrogenito-perineal syndrome, elephantiasis of the penis and scrotum, rectal stenosis, and plastic induration of the penis. Esthiomene is characterized by a chronic ...
2009, Thomas P. Habif, Clinical Dermatology E-Book, Elsevier Health Sciences, →ISBN, page 409:
[...] edema (elephantiasis) of the female external genitals is a late manifestation of lymphatic obstruction. The enlargement, thickening, and fibrosis of the labia is termed esthiomene. Penile and/or scrotal edema and gross distortion of the penis ...
2019, Neena Khanna, Illustrated Synopsis of Dermatology & Sexually Transmitted Diseases-Ebk, Elsevier India, →ISBN, page 322:
(B) Tertiary stage: Esthiomene characterized by elephantiasis and chronic ulceration of vulva.
Usage notes
Rarely also used of elephantiasis of the penis or scrotum.[1]
References
↑ 1.01.1King Holmes, P. Sparling, Walter Stamm, Peter Piot, Judith Wasserheit, Lawrence Corey, Myron Cohen, Sexually Transmitted Diseases, Fourth Edition, McGraw Hill Professional (2007, →ISBN), page 600: "Esthiomene (Greek, “eating away”), a primary infection affecting the lymphatics of the scrotum, penis, or vulva, "