synthetic lethality
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English
Noun
synthetic lethality (usually uncountable, plural synthetic lethalities)
- (genetics) A type of genetic interaction in which two (or more) mutations which are not lethal when occurring singly in a cell are lethal when they occur together in the same cell.
References
- Maloy, Stanley with French-Mischo, Stephanie (2002 July 16) “Synthetic Lethal Mutations”, in Microbial Genetics, San Diego State University, archived from the original on 13 May 2003
- Le Meur, Nolwenn with Gentleman, Robert (2008 September 12) “Modeling synthetic lethality”, in Genome Biology, volume 9, , archived from the original on 14 October 2012, page R135