pyrrolobenzodiazepine
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English
Etymology
From pyrrol + -o- + benzo- + di- + azepine.
Noun
pyrrolobenzodiazepine (plural pyrrolobenzodiazepines)
- (pharmacology) A class of compounds with antibiotic and anti-tumor properties.
- 2015 August 19, Maria Mellinas-Gomez et al., “Activity of the DNA minor groove cross-linking agent SG2000 (SJG-136) against canine tumours”, in BMC Veterinary Research, volume 11, :
- SG2000 (SJG-136, NSC694501) is a rationally designed pyrrolobenzodiazepine dimer which interacts sequence selectively in the minor groove of DNA.