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This is an exceptionally reserved code, included as part of ISO 3166-1 on the request of the Universal Postal Union for the purpose of assigning a stamp issuing area, and is not endorsed for general use by the ISO outside of that purpose.
2018, Gollins S et al., “A prospective phase II study of pre-operative chemotherapy then short-course radiotherapy for high risk rectal cancer: COPERNICUS”, in British Journal of Cancer:
Current UK practice, supported by NICE guidance is to complete local pelvic treatment with surgery±pre-operative radiotherapy, before considering systemic adjuvant chemotherapy (AC)