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From Ancient Greekπολύγονον(polúgonon, “knotweed”) from πολύς(polús, “many”) + γόνυ(gónu, “knee”) (though γόνος(gónos, “offspring”) has been suggested- the "knots" in "knotweed" are enlarged joints like knees, and it's certainly a prolific weed, so either derivation is plausible).
Hyam, R., Pankhurst, R.J. (1995) Plants and their names : a concise dictionary, Oxford: Oxford University Press, →ISBN p. 404.
Coombes, Allen J. (1994) Dictionary of Plant Names, London: Hamlyn Books, →ISBN p. 148.
Martinius, Matthias (1655) Lexicon Philologicum præcipue etymologicum et sacrum (in Latin), T. M. Goetzenius. Polygonum.
Costea, Mihai, Tardif, François J., Hinds, Harold R. (1982 onwards) “Polygonum”, in Flora of North America Editorial Committee, editor, Flora of North America (online), eFloras.org