prehepatic
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English
Etymology
Adjective
prehepatic (not comparable)
- (anatomy) anterior to the liver.
- (anatomy, biochemistry) upstream of the liver in the circulation of the hepatic portal system; and thus, before the metabolic effect of the liver.
- 2015 June 12, Jeanne Mendell et al., “The Effect of Rifampin on the Pharmacokinetics of Edoxaban in Healthy Adults”, in Clinical Drug Investigation, volume 35, :
- Administration of intravenous edoxaban with and without rifampin may have differentiated the prehepatic versus hepatic effects of rifampin on parent and metabolite exposure.