sympatheticolytic

From sympathetic +‎ -o- +‎ -lytic.

sympatheticolytic (comparative more sympatheticolytic, superlative most sympatheticolytic)

1. Alternative form of sympatholytic
   • 1936, A Manual of Pharmacology and Its Applications to Therapeutics and Toxicology, page 434:

     Other pharmacologic actions include the cyanosis of the coxcomb, rather slight sympatheticolytic (epinephrine-reversal) action, slight rise in blood pressure, depression of frog’s heart, mydriasis in rabbits (M. E. Davis, Adair, Chen and Swanson, 1935).

   • 1949, British Journal of Physical Medicine, page 12:

     Our own observations—particularly in those experiments in which marked variations of the electrocardiogram during the hot-air bath were reduced or disappeared after application of a sympatheticolytic drug—often showed typical sympatheticotonic variations during the pyrexia and vagotonic variations after its completion (Fig. 2).

   • 2012 April 24, Mervyn J. Eadie, “Chapter 6: The Treatment of Migraine”, in Headache: Through the Centuries, Oxford University Press, →ISBN, page 170:

     At this time, the rationale for the use of ergotamine was that, contrary to the interpretation that had prevailed in earlier years, migraine headache depended on excessive rather than decreased sympathetic activity, and that ergotamine had a sympatheticolytic rather than a sympathomimetic effect.

sympatheticolytic (plural sympatheticolytics)

1. Alternative form of sympatholytic
   • 1940, British Chemical and Physiological Abstracts, page 248:

     Cocaine diminished considerably the hypertensive effect, which is not reversed by the sympatheticolytic F. 883.

   • 1951, Ophthalmic Literature, volume 5, page 705:

     Combined therapy is recommended—“priscol” (benzyl-imidazoline) a sympatheticolytic, 20 mg. daily, and “dilvaséne”, a synthetic parasympatheticomimetic, 50 mg. daily, both by mouth, in three or four divided doses.

   • 1953, The Year Book of Neurology, Psychiatry, and Neurosurgery, page 373:

     Drugs used were hydergine, a sympatheticolytic and vasodilator combination of dihydroergocornine, dihydroergocristine and dihydroergokryptine, and bellergal, a combination of a parasympatheticolytic bellafoline, a sympatheticolytic ergotamine tartrate and a sedative phenobarbitone.

   • 1958, Review of Czechoslovak Medicine, volume 4, page 116:

     Experiments with the administration of 0.75 mg. ergotamine subcutaneously did not confirm the assumed importance of sympatheticolytics in the inhibition of mucus secretion.

   • 1968, Marcel Monnier, Functions of the Nervous System, page 587:

     Flemming (1954) found, after instillation of drugs into the conjunctival sac, that sympathetico-memetics and parasympatheticolytics increase the flicker frequency, while parasympathetico-memetics and sympatheticolytics reduce it. (Alpern and Jampel, 1959).

   • 1979, Endocrinologie, volume 17, page 86:

     In this therapy every pharmacodynamic agent acts predominantly at the level of the pathogenic link affected: the sympatheticolytics at the level of vasoconstriction, the adrenocortical mixture at the level of vasodilatation.