Appears to be a coinage in Japanese composed of Middle Chinese-derived roots, as a compound of 毒 (doku, “poison”) + 婦 (fu, “woman; wife”). First cited...
【<span class="searchmatch">毒婦</span>】 [noun] [from 1833] a wicked woman, evil woman, she-devil [noun] a vamp, a Jezebel, a temptress...