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A PIE interrogative-indefinite paradigm built from the stems *kʷi- and *kʷe- (parallel to anaphoric *i-, *e-), the former on nominative and accusative cases of all genders, the latter elsewhere, with no distinction of feminine forms, mostly "human" – "non-human". A stem *kʷo-, an o-stem adjective, with its corresponding feminine *kʷeh₂-, was originally separate, but in most languages there was some conflation with the other two, as it is from this function that the relative pronoun evolves. Ultimately from *kʷ-.
Proto-Italic: *kʷoi (see there for further descendants)
References
^ Sihler, Andrew L. (1995) New Comparative Grammar of Greek and Latin, Oxford, New York: Oxford University Press, →ISBN
^ De Vaan, Michiel (2008) Etymological Dictionary of Latin and the other Italic Languages (Leiden Indo-European Etymological Dictionary Series; 7), Leiden, Boston: Brill, →ISBN, page 510
^ De Vaan, Michiel (2008) Etymological Dictionary of Latin and the other Italic Languages (Leiden Indo-European Etymological Dictionary Series; 7), Leiden, Boston: Brill, →ISBN